BD-PB3850

NCOA4 (14W6) Mouse Monoclonal Antibody

Nuclear receptor coactivator 4, NCoA-4, Androgen receptor coactivator 70 kDa protein, 70 kDa AR-activator, 70 kDa androgen receptor coactivator, Androgen receptor-associated protein of 70 kDa, Ret-activating protein ELE1, NCOA4, ARA70, ELE1, RFG

常规抗体

WB

Human

NP_001138732.1;NP_001138733.1;NP_001138734.1;NP_001138735.1;NP_005428.1

Q13772

Purified His-tagged NCOA4 protein(Fragment) was used to produced this monoclonal antibody.

WB~~1:500~1000

70kDa

IgM

This gene encodes an androgen receptor coactivator. The encoded protein interacts with the androgen receptor in a ligand-dependent manner to enhance its transcriptional activity. Chromosomal translocations between this gene and the ret tyrosine kinase gene, also located on chromosome 10, have been associated with papillary thyroid carcinoma. Alternatively spliced transcript variants have been described. Pseudogenes are present on chromosomes 4, 5, 10, and 14.

Widely expressed. Also detected in adipose tissues and in different cell lines. Isoform Beta is only expressed in testis

现货