产品名称
MS4A1/CD20 (3I3) Mouse Monoclonal Antibody (C-term) (Ascites)
别名
B-lymphocyte antigen CD20, B-lymphocyte surface antigen B1, Bp35, Leukocyte surface antigen Leu-16, Membrane-spanning 4-domains subfamily A member 1, CD20, MS4A1, CD20
Human Gene ID
NP_068769.2;NP_690605.1
Human Swissprot No.
P11836
特异性
This MS4A1/CD20 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 266-294 amino acids from the C-terminal region of human MS4A1/CD20.
背景介绍
This gene encodes a member of the membrane-spanning 4A
gene family. Members of this nascent protein family are
characterized by common structural features and similar intron/exon
splice boundaries and display unique expression patterns among
hematopoietic cells and nonlymphoid tissues. This gene encodes a
B-lymphocyte surface molecule which plays a role in the development
and differentiation of B-cells into plasma cells. This family
member is localized to 11q12, among a cluster of family members.
Alternative splicing of this gene results in two transcript
variants which encode the same protein.
组织表达
Expressed on B-cells.
细胞定位
Cell membrane; Multi-pass membrane protein. Cell membrane; Lipid-anchor. Note=Constitutively associated with membrane rafts.