产品名称
RYK (5F17) Mouse Monoclonal Antibody (ascites)
别名
Tyrosine-protein kinase RYK, RYK, JTK5A
Human Gene ID
NP_001005861.1;NP_002949.2
Human Swissprot No.
P34925
特异性
This RYK monoclonal antibody is generated from mouse immunized with RYK recombinant protein.
背景介绍
The protein encoded by this gene is an atypical member of
the family of growth factor receptor protein tyrosine kinases,
differing from other members at a number of conserved residues in
the activation and nucleotide binding domains. This gene product
belongs to a subfamily whose members do not appear to be regulated
by phosphorylation in the activation segment. It has been suggested
that mediation of biological activity by recruitment of a
signaling-competent auxiliary protein may occur through an as yet
uncharacterized mechanism. Two alternative splice variants have
been identified, encoding distinct isoforms.
组织表达
Observed in all the tissues examined.
细胞定位
Membrane; Single-pass type I membrane protein. Nucleus. Cytoplasm. Note=In cells that have undergone neuronal differentiation, the C-terminal cleaved part is translocated from the cytoplasm to the nucleus.
