BD-PB3817-ELAVL1 (3D9) Mouse Monoclonal Antibody-现货抗体产品库武汉枢密脑科学技术有限公司

ELAVL1 (3D9) Mouse Monoclonal Antibody

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产品基本信息

产品货号

BD-PB3817

产品名称

ELAVL1 (3D9) Mouse Monoclonal Antibody

别名

ELAV-like protein 1, Hu-antigen R, HuR, ELAVL1, HUR

类别

常规抗体

推荐应用

反应种属

Human

Human Gene ID

NP_001410.2

Human Swissprot No.

Q15717

特异性

This ELAVL1 monoclonal antibody is generated from mouse immunized with ELAVL1 recombinant protein.

稀释度

WB~~1:1000;IF~~1:10~50

预测分子量

36kDa

同种型

IgG1,K

背景介绍

The protein encoded by this gene is a member of the ELAVL protein family. This encoded protein contains 3 RNA-binding domains and binds cis-acting AU-rich elements. It destabilizes mRNAs and thereby regulates gene expression.

组织表达

Ubiquitous. Detected in brain, liver, thymus and muscle.

细胞定位

Cytoplasm. Nucleus. Cytoplasm, Stress granule {ECO:0000250|UniProtKB:P70372}. Note=Translocates into the cytoplasm following phosphorylation by MAPKAPK2 (PubMed:14517288) Likewise, phosphorylation by PRKCD promotes translocation from the nucleus into the cytoplasm, where it is associated with free and cytoskeleton-bound polysomes (PubMed:18285462).Localizes to the stress granules in the presence of PLEKHN1 (By similarity) {ECO:0000250|UniProtKB:P70372, ECO:0000269|PubMed:14517288, ECO:0000269|PubMed:18285462}

期货

现货

All lanes : Anti- at 1:1000 dilution Lane 1: 293 whole cell lysate Lane 2: Jurkat whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 36 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

Confocal immunofluorescent analysis of ELAVL1 Antibody with NCI-H460 cell followed by Alexa Fluor® 488-conjugated goat anti-mouse lgG (green). DAPI was used to stain the cell nuclear (blue).