BD-PB3811

NLRP12 (6C12) Mouse Monoclonal Antibody

NACHT, LRR and PYD domains-containing protein 12, Monarch-1, PYRIN-containing APAF1-like protein 7, Regulated by nitric oxide, NLRP12, NALP12, PYPAF7, RNO

常规抗体

WB

Human, Mouse

NP_001264055.1;NP_001264058.1;NP_653288.1

P59046

This NLRP12 monoclonal antibody is generated from mouse immunized with NLRP12 recombinant protein.

WB~~1:500

120kDa

IgM,K

This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Alternatively spliced transcript variants encoding distinct isoforms have been described but the full-length nature of some of these has not been determined.

Detected only in peripheral blood leukocytes, predominantly in eosinophils and granulocytes, and at lower levels in monocytes.

Cytoplasm.

现货