产品名称
IHH (5A5) Mouse Monoclonal Antibody (C-term) (Ascites)
别名
Indian hedgehog protein, IHH, HHG-2, Indian hedgehog protein N-product, Indian hedgehog protein C-product, IHH
Human Gene ID
NP_002172.2
Human Swissprot No.
Q14623
特异性
This IHH Monoclonal antibody is generated from mouses immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human IHH.
背景介绍
Intercellular signal essential for a variety of patterning events during development. Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. Implicated in endochondral ossification: may regulate the balance between growth and ossification of the developing bones. Induces the expression of parathyroid hormone-related protein (PTHRP).
组织表达
Expressed in embryonic lung, and in adult kidney and liver
细胞定位
[Indian hedgehog protein N-product]: Cell membrane; Lipid-anchor; Extracellular side. Note=The N-terminal peptide remains associated with the cell surface. Cell membrane.