产品名称
ADX Rabbit Polyclonal Antibody
别名
Adrenodoxin, mitochondrial (Adrenal ferredoxin) (Ferredoxin-1) (Hepatoredoxin)
蛋白名称
Adrenodoxin, mitochondrial (Adrenal ferredoxin) (Ferredoxin-1) (Hepatoredoxin)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2230
Human Swissprot No.
P10109
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P10109/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=14148
Mouse Swissprot No.
P46656
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/P46656/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=29189
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/P24483/entry
特异性
This antibody detects endogenous levels of ADX at Human, Mouse,Rat
稀释度
WB 1:500-2000 IHC 1:50-200
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Highest levels in the adrenal gland (at protein level). Also detected in kidney and testis (at protein level).
细胞定位
Mitochondrion matrix .
功能
Essential for the synthesis of various steroid hormones . Participates in the reduction of mitochondrial cytochrome P450 for steroidogenesis . Transfers electrons from adrenodoxin reductase to CYP11A1, a cytochrome P450 that catalyzes cholesterol side-chain cleavage . Does not form a ternary complex with adrenodoxin reductase and CYP11A1 but shuttles between the two enzymes to transfer electrons (By similarity).
