产品名称
P2RX7 Rabbit Polyclonal Antibody
别名
P2X purinoceptor 7 (P2X7) (ATP receptor) (P2Z receptor) (Purinergic receptor)
蛋白名称
P2X purinoceptor 7 (P2X7) (ATP receptor) (P2Z receptor) (Purinergic receptor)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=5027
Human Swissprot No.
Q99572
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q99572/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=18439
Mouse Swissprot No.
Q9Z1M0
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9Z1M0/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=29665
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q64663/entry
特异性
This antibody detects endogenous levels of P2RX7 at Human, Mouse,Rat
稀释度
WB 1:500-2000 IHC 1:50-200
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Widely expressed with highest levels in brain and immune tissues.
细胞定位
Cell membrane ; Multi-pass membrane protein .
功能
Receptor for ATP that acts as a ligand-gated ion channel. Responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Could function in both fast synaptic transmission and the ATP-mediated lysis of antigen-presenting cells. In the absence of its natural ligand, ATP, functions as a scavenger receptor in the recognition and engulfment of apoptotic cells .
