产品名称
PANX1 Rabbit Polyclonal Antibody
基因名称
PANX1 MRS1 UNQ2529/PRO6028
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=24145
Human Swissprot No.
Q96RD7
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q96RD7/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=55991
Mouse Swissprot No.
Q9JIP4
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9JIP4/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=315435
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/P60570/entry
特异性
This antibody detects endogenous levels of PANX1 at Human, Mouse,Rat
稀释度
WB 1:500-2000 IHC 1:50-200
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Widely expressed (PubMed:30918116). Highest expression is observed in oocytes and brain (PubMed:30918116). Detected at very low levels in sperm cells (PubMed:30918116).
细胞定位
Cell membrane ; Multi-pass membrane protein . Cell junction, gap junction . Endoplasmic reticulum membrane ; Multi-pass membrane protein .
功能
Structural component of the gap junctions and the hemichannels involved in the ATP release and nucleotide permeation . May play a role as a Ca(2+)-leak channel to regulate ER Ca(2+) homeostasis . Plays a critical role in oogenesis .
