产品名称
WNT2B Rabbit Polyclonal Antibody
别名
Protein Wnt-2b (Protein Wnt-13)
蛋白名称
Protein Wnt-2b (Protein Wnt-13)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=7482
Human Swissprot No.
Q93097
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q93097/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=22414
Mouse Swissprot No.
O70283
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/O70283/entry
特异性
This antibody detects endogenous levels of WNT2B at Human, Mouse
稀释度
WB 1:500-2000 IHC 1:50-200
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Isoform 1 is expressed in adult heart, brain, placenta, lung, prostate, testis, ovary, small intestine and colon. In the adult brain, it is mainly found in the caudate nucleus, subthalamic nucleus and thalamus. Also detected in fetal brain, lung and kidney. Isoform 2 is expressed in fetal brain, fetal lung, fetal kidney, caudate nucleus, testis and cancer cell lines.
细胞定位
Secreted, extracellular space, extracellular matrix . Secreted .
功能
Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt/beta-catenin signaling pathway. Plays a redundant role in embryonic lung development.
