产品名称
S43A3 Rabbit Polyclonal Antibody
别名
Solute carrier family 43 member 3 (Protein FOAP-13)
蛋白名称
Solute carrier family 43 member 3 (Protein FOAP-13)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=29015
Human Swissprot No.
Q8NBI5
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q8NBI5/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=58207
Mouse Swissprot No.
A2AVZ9
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/A2AVZ9/entry
特异性
This antibody detects endogenous levels of S43A3 at Human, Mouse
稀释度
WB 1:500-2000 IHC 1:50-200
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Widely expressed with highest levels in the liver and lung, followed by the pancreas (PubMed:26455426). Highly expressed in macrophages (Ref.1).
细胞定位
Basolateral cell membrane ; Multi-pass membrane protein .
功能
Sodium-independent purine-selective nucleobase transporter which mediates the equilibrative transport of extracellular purine nucleobases such as adenine, guanine and hypoxanthine . May regulate fatty acid (FA) transport in adipocytes, acting as a positive regulator of FA efflux and as a negative regulator of FA uptake (By similarity). ; [Isoform 1]: Sodium-independent purine-selective nucleobase transporter which mediates the equilibrative transport of extracellular purine nucleobase adenine . Mediates the influx and efflux of the purine nucleobase analog drug 6-mercaptopurine across the membrane . ; [Isoform 2]: Sodium-independent purine-selective nucleobase transporter which mediates the equilibrative transport of extracellular purine nucleobase adenine . Mediates the influx and efflux of the purine nucleobase analog drug 6-mercaptopurine across the membrane .