产品名称
REEP5 Rabbit Polyclonal Antibody
别名
Receptor expression-enhancing protein 5 (Polyposis locus protein 1) (Protein TB2)
基因名称
REEP5 C5orf18 DP1 TB2
蛋白名称
Receptor expression-enhancing protein 5 (Polyposis locus protein 1) (Protein TB2)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=7905
Human Swissprot No.
Q00765
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q00765/entry
Mouse Swissprot No.
Q60870
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q60870/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=364838
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/B2RZ37/entry
特异性
This antibody detects endogenous levels of REEP5 at Human, Mouse,Rat
稀释度
WB 1:500-2000 IHC 1:50-200
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Expressed in heart (at protein level) (PubMed:32075961). Expressed in circumvallate papillae and testis (PubMed:16720576).
细胞定位
Endoplasmic reticulum membrane ; Multi-pass membrane protein . Sarcoplasmic reticulum membrane ; Multi-pass membrane protein . Localizes to endoplasmic reticulum tubular network (PubMed:23969831). In cardiomyocytes, localizes to the junctional sarcoplasmic reticulum membrane which is closely tethered to the cell membrane and contractile machinery (By similarity). .
功能
Plays an essential role in heart function and development by regulating the organization and function of the sarcoplasmic reticulum in cardiomyocytes.
