产品名称
TM1L1 Rabbit Polyclonal Antibody
蛋白名称
TOM1-like protein 1 (Src-activating and signaling molecule protein) (Target of Myb-like protein 1)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
O75674
Human Swissprot Link
https://www.uniprot.org/uniprotkb/O75674/entry
Mouse Swissprot No.
Q923U0
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q923U0
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941F1LM81
免疫原
Synthesized peptide derived from part region of human protein
特异性
TM1L1 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
function:Probable adapter protein involved in signaling pathways. Interacts with the SH2 and SH3 domains of various signaling proteins when it is phosphorylated. May promotes FYN activation, possibly by disrupting intramolecular SH3-dependent interactions.,PTM:Phosphorylated on tyrosines by FYN (By similarity). Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the TOM1 family.,similarity:Contains 1 GAT domain.,similarity:Contains 1 VHS domain.,subunit:Interacts with FYN, GRB2 and PIK3R1 when phosphorylated.,
细胞定位
Golgi apparatus, Golgi stack. Endosome membrane . Cytoplasm . Membrane ; Peripheral membrane protein ; Cytoplasmic side . A small proportion is membrane-associated. .
功能
function:Probable adapter protein involved in signaling pathways. Interacts with the SH2 and SH3 domains of various signaling proteins when it is phosphorylated. May promotes FYN activation, possibly by disrupting intramolecular SH3-dependent interactions.,PTM:Phosphorylated on tyrosines by FYN (By similarity). Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the TOM1 family.,similarity:Contains 1 GAT domain.,similarity:Contains 1 VHS domain.,subunit:Interacts with FYN, GRB2 and PIK3R1 when phosphorylated.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.