产品名称
CSFR (Phospho Tyr921) Rabbit Polyclonal Antibody
别名
Macrophage colony-stimulating factor 1 receptor (CSF-1 receptor) (CSF-1-R) (CSF-1R) (M-CSF-R) (EC 2.7.10.1) (Proto-oncogene c-Fms) (CD antigen CD115)
蛋白名称
Macrophage colony-stimulating factor 1 receptor (CSF-1 receptor) (CSF-1-R) (CSF-1R) (M-CSF-R) (EC 2.7.10.1) (Proto-oncogene c-Fms) (CD antigen CD115)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1436
Human Swissprot No.
P07333
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P07333/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=12978
Mouse Swissprot No.
P09581
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/P09581/entry
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q00495/entry
特异性
This antibody detects endogenous levels of CSFR (Phospho Tyr921) Rabbit pAb at Human, Mouse,Rat
稀释度
WB 1:500-2000 IHC 1:50-200
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Expressed in bone marrow and in differentiated blood mononuclear cells.
细胞定位
Cell membrane; Single-pass type I membrane protein.
功能
catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,function:Protein tyrosine-kinase transmembrane receptor for CSF1 and IL34.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 5 Ig-like C2-type (immunoglobulin-like) domains.,subunit:Interacts with INPPL1/SHIP2 and THOC5.,tissue specificity:Expressed in bone marrow and in differentiated blood mononuclear cells.,