产品名称
TSP3 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
P49746
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P49746/entry
Mouse Swissprot No.
Q05895
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q05895
免疫原
Synthesized peptide derived from part region of human protein
特异性
TSP3 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
thrombospondin 3(THBS3) Homo sapiens The protein encoded by this gene belongs to the thrombospondin family. Thrombospondin family members are adhesive glycoproteins that mediate cell-to-cell and cell-to-matrix interactions. This protein forms a pentameric molecule linked by a single disulfide bond. This gene shares a common promoter with metaxin 1. Alternate splicing results in coding and non-coding transcript variants. [provided by RefSeq, Nov 2011],
组织表达
Lung,PCR rescued clones,Retina,Synovial membrane,
细胞定位
extracellular region,perinuclear region of cytoplasm,
信号通路
TGF-beta;Focal adhesion;ECM-receptor interaction;
功能
function:Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Can bind to fibrinogen, fibronectin, laminin and type V collagen.,similarity:Belongs to the thrombospondin family.,similarity:Contains 1 TSP C-terminal (TSPC) domain.,similarity:Contains 1 TSP N-terminal (TSPN) domain.,similarity:Contains 4 EGF-like domains.,similarity:Contains 8 TSP type-3 repeats.,subunit:Oligomer; disulfide-linked.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
