产品名称
PERP Rabbit Polyclonal Antibody
基因名称
PERP KCP1 KRTCAP1 PIGPC1 THW
蛋白名称
p53 apoptosis effector related to PMP-22 (Keratinocyte-associated protein 1) (KCP-1) (P53-induced protein PIGPC1) (Transmembrane protein THW)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=64065
Human Swissprot No.
Q96FX8
Human Swissprot Link
https://www.uniprot.org/uniprot/Q96FX8
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=64058
Mouse Swissprot No.
Q9JK95
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9JK95/entry
特异性
This antibody detects endogenous levels of PERP at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Expressed in skin, heart, placental, liver, pancreas, keratinocytes and dermal fibroblasts.
细胞定位
Cell junction, desmosome . Cell membrane ; Multi-pass membrane protein . Associated with desmosomes (By similarity). Colocalizes with KRT14 in the cell membrane (PubMed:31898316). .
功能
Component of intercellular desmosome junctions. Plays a role in stratified epithelial integrity and cell-cell adhesion by promoting desmosome assembly. ; Plays a role as an effector in the TP53-dependent apoptotic pathway.
