产品名称
Plexin A1 Rabbit Polyclonal Antibody
蛋白名称
Plexin-A1 (Semaphorin receptor NOV)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=5361
Human Swissprot No.
Q9UIW2
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9UIW2
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=18844
Mouse Swissprot No.
P70206
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/P70206/entry
特异性
This antibody detects endogenous levels of Plexin A1 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Detected in fetal brain, lung, liver and kidney.
细胞定位
Cell membrane ; Single-pass type I membrane protein .
功能
Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm (By similarity).
