产品名称
FLAP Rabbit Polyclonal Antibody
蛋白名称
Arachidonate 5-lipoxygenase-activating protein (FLAP) (MK-886-binding protein)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=241
Human Swissprot No.
P20292
Human Swissprot Link
https://www.uniprot.org/uniprot/P20292
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=11690
Mouse Swissprot No.
P30355
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/P30355/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=29624
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/P20291/entry
特异性
This antibody detects endogenous levels of FLAP at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Nucleus membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
功能
Required for leukotriene biosynthesis by ALOX5 (5-lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes.
