产品名称
TWEAKR/FN14 Rabbit Polyclonal Antibody
蛋白名称
Tumor necrosis factor receptor superfamily member 12A (Fibroblast growth factor-inducible immediate-early response protein 14) (FGF-inducible 14) (Tweak-receptor) (TweakR) (CD antigen CD266)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=51330
Human Swissprot No.
Q9NP84
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9NP84
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=27279
Mouse Swissprot No.
Q9CR75
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9CR75/entry
特异性
This antibody detects endogenous levels of TWEAKR/FN14 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Highly expressed in heart, placenta and kidney. Intermediate expression in lung, skeletal muscle and pancreas.
细胞定位
Membrane; Single-pass type I membrane protein.
功能
Receptor for TNFSF12/TWEAK. Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins.