产品名称
GLS2 Rabbit Polyclonal Antibody
蛋白名称
Glutaminase liver isoform, mitochondrial (GLS) (EC 3.5.1.2) (L-glutaminase) (L-glutamine amidohydrolase)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=27165
Human Swissprot No.
Q9UI32
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9UI32
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=216456
Mouse Swissprot No.
Q571F8
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q571F8/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=192268
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/P28492/entry
特异性
This antibody detects endogenous levels of GLS2 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Highly expressed in liver. Expressed in brain and pancreas. Not observed in heart, placenta, lung, skeletal muscle and kidney. Expression is significantly reduced in hepatocellular carcinomas.
功能
Plays an important role in the regulation of glutamine catabolism. Promotes mitochondrial respiration and increases ATP generation in cells by catalyzing the synthesis of glutamate and alpha-ketoglutarate. Increases cellular anti-oxidant function via NADH and glutathione production. May play a role in preventing tumor proliferation.
