产品名称
Lubricin/MSF Rabbit Polyclonal Antibody
蛋白名称
Proteoglycan 4 (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Cleaved into: Proteoglycan 4 C-terminal part]
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10216
Human Swissprot No.
Q92954
Human Swissprot Link
https://www.uniprot.org/uniprot/Q92954
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=96875
Mouse Swissprot No.
Q9JM99
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9JM99/entry
特异性
This antibody detects endogenous levels of Lubricin/MSF at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Highly expressed in synovial tissue, cartilage and liver and weakly in heart and lung. Isoform B is expressed in kidney, lung, liver, heart and brain. Isoform C and isoform D are widely expressed.
功能
Plays a role in boundary lubrication within articulating joints. Prevents protein deposition onto cartilage from synovial fluid by controlling adhesion-dependent synovial growth and inhibiting the adhesion of synovial cells to the cartilage surface.; Isoform F plays a role as a growth factor acting on the primitive cells of both hematopoietic and endothelial cell lineages.
