产品名称
TCPG Rabbit Polyclonal Antibody
蛋白名称
T-complex protein 1 subunit gamma (TCP-1-gamma) (CCT-gamma) (hTRiC5)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
P49368
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P49368/entry
Mouse Swissprot No.
P80318
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P80318
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q6P502
免疫原
Synthesized peptide derived from part region of human protein
特异性
TCPG Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants have been characterized for this gene. In addition, a pseudogene of this gene has been found on chromosome 8. [provided by RefSeq, Aug 2010],
组织表达
Brain,Cajal-Retzius cell,Cerebellum,Epithelium,Hepatoma,Kidney,Lung
功能
function:Molecular chaperone; assist the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. Plays a role in the assembly of the von Hippel-Lindau ubiquitination complex.,similarity:Belongs to the TCP-1 chaperonin family.,subunit:Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter. Interacts with PACRG.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
