产品名称
CENPB Rabbit Polyclonal Antibody
蛋白名称
Major centromere autoantigen B (Centromere protein B) (CENP-B)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1059
Human Swissprot No.
P07199
Human Swissprot Link
https://www.uniprot.org/uniprot/P07199
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=12616
Mouse Swissprot No.
P27790
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/P27790/entry
特异性
This antibody detects endogenous levels of CENPB at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Nucleus . Chromosome, centromere .
功能
Interacts with centromeric heterochromatin in chromosomes and binds to a specific 17 bp subset of alphoid satellite DNA, called the CENP-B box . May organize arrays of centromere satellite DNA into a higher-order structure which then directs centromere formation and kinetochore assembly in mammalian chromosomes (Probable).