产品名称
Perilipin-1 Rabbit Polyclonal Antibody
蛋白名称
Perilipin-1 (Lipid droplet-associated protein)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=5346
Human Swissprot No.
O60240
Human Swissprot Link
https://www.uniprot.org/uniprot/O60240
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=103968
Mouse Swissprot No.
Q8CGN5
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8CGN5/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=25629
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/P43884/entry
特异性
This antibody detects endogenous levels of Perilipin-1 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Detected in adipocytes from white adipose tissue (at protein level) (PubMed:27832861). Detected in visceral adipose tissue and mammary gland (PubMed:9521880).
细胞定位
Endoplasmic reticulum . Lipid droplet . Lipid droplet surface-associated. .
功能
Modulator of adipocyte lipid metabolism. Coats lipid storage droplets to protect them from breakdown by hormone-sensitive lipase (HSL). Its absence may result in leanness. Plays a role in unilocular lipid droplet formation by activating CIDEC. Their interaction promotes lipid droplet enlargement and directional net neutral lipid transfer. May modulate lipolysis and triglyceride levels.