产品名称
TBX15 Rabbit Polyclonal Antibody
蛋白名称
T-box transcription factor TBX15 (T-box protein 15) (T-box transcription factor TBX14) (T-box protein 14)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q96SF7
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q96SF7/entry
Mouse Swissprot No.
O70306
Mouse Swissprot Link
http://www.uniprot.org/uniprot/O70306
免疫原
Synthesized peptide derived from part region of human protein
特异性
TBX15 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
T-box 15(TBX15) Homo sapiens This gene belongs to the T-box family of genes, which encode a phylogenetically conserved family of transcription factors that regulate a variety of developmental processes. All these genes contain a common T-box DNA-binding domain. Mutations in this gene are associated with Cousin syndrome.[provided by RefSeq, Oct 2009],
组织表达
Liver,PCR rescued clones,
功能
disease:Defects in TBX15 are the cause of Cousin syndrome [MIM:260660]; also called craniofacial dysmorphism, hypoplasia of scapula and pelvis, and short stature. Cousin syndrome is defined as pelviscapular dysplasia with epiphyseal abnormalities, congenital dwarfism and facial dysmorphy (frontal bossing, hypertelorism, narrow palpebral fissures, deep set globes, strabismus, low-set posteriory rotated and unusually formed external ears, dysplasia of conchae, small chin, short neck with redundant skin folds, and a low hairline). Intelligence may vary from normal to moderately impaired. Radiographic features comprise aplasia of the body of the scapula, hypoplasia of the iliac bone, humeroradial synosthosis, dislocation of the femoral heads, and moderate brachydactyly.,function:Probable transcriptional regulator involved in developmental processes.,similarity:Contains 1 T-box DNA-binding domain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
