产品名称
IPYR Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/5464
Human Swissprot No.
Q15181
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q15181/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/67895
Mouse Swissprot No.
Q9D819
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9D819
免疫原
Synthesized peptide derived from human IPYR AA range: 162-212
特异性
This antibody detects endogenous levels of IPYR at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is a member of the inorganic pyrophosphatase (PPase) family. PPases catalyze the hydrolysis of pyrophosphate to inorganic phosphate, which is important for the phosphate metabolism of cells. Studies of a similar protein in bovine suggested a cytoplasmic localization of this enzyme. [provided by RefSeq, Jul 2008],
组织表达
Expressed ubiquitously.
功能
catalytic activity:Diphosphate + H(2)O = 2 phosphate.,cofactor:Binds 4 magnesium ions per subunit. Other metal ions can support activity, but at a lower rate. Two magnesium ions are required for the activation of the enzyme and are present before substrate binds, two additional magnesium ions form complexes with substrate and product.,similarity:Belongs to the PPase family.,subunit:Homodimer.,tissue specificity:Expressed ubiquitously.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.