产品名称
AP5Z1/SPG48 Rabbit Polyclonal Antibody
基因名称
AP5Z1 KIAA0415 SPG48
蛋白名称
AP-5 complex subunit zeta-1 (Adapter-related protein complex 5 zeta subunit) (Zeta5)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=9907
Human Swissprot No.
O43299
Human Swissprot Link
https://www.uniprot.org/uniprot/O43299
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=231855
Mouse Swissprot No.
Q3U829
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q3U829/entry
特异性
This antibody detects endogenous levels of AP5Z1/SPG48 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Cytoplasm . Nucleus . By SDS-PAGE, 2 isoforms have been observed, the shorter seems to be predominantly nuclear and the longer is mostly cytoplasmic. .
功能
As part of AP-5, a probable fifth adaptor protein complex it may be involved in endosomal transport. According to PubMed:20613862 it is a putative helicase required for efficient homologous recombination DNA double-strand break repair.
