产品名称
CDCA5 Rabbit Polyclonal Antibody
蛋白名称
Sororin (Cell division cycle-associated protein 5) (p35)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=113130
Human Swissprot No.
Q96FF9
Human Swissprot Link
https://www.uniprot.org/uniprot/Q96FF9
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=67849
Mouse Swissprot No.
Q9CPY3
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9CPY3/entry
特异性
This antibody detects endogenous levels of CDCA5 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Nucleus . Chromosome . Cytoplasm . Associates with nuclear chromatin from S phase until metaphase and is released in the cytoplasm upon nuclear envelope breakdown.
功能
Regulator of sister chromatid cohesion in mitosis stabilizing cohesin complex association with chromatin. May antagonize the action of WAPL which stimulates cohesin dissociation from chromatin. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair. Required for efficient DNA double-stranded break repair.
