产品名称
THSD7A Rabbit Polyclonal Antibody
蛋白名称
Thrombospondin type-1 domain-containing protein 7A
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=221981
Human Swissprot No.
Q9UPZ6
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9UPZ6
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=330267
Mouse Swissprot No.
Q69ZU6
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q69ZU6/entry
特异性
This antibody detects endogenous levels of THSD7A at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Detected on kidney podocytes along the glomerular capillary wall (at protein level).
细胞定位
[Thrombospondin type-1 domain-containing protein 7A]: Cell membrane ; Single-pass type I membrane protein . Cell projection . Detected on podocyte foot processes. .; [Thrombospondin type-1 domain-containing protein 7A, soluble form]: Secreted . Proteolytic cleavage in the extracellular region generates a 210 kDa soluble form. .
功能
[Thrombospondin type-1 domain-containing protein 7A]: Plays a role in actin cytoskeleton rearrangement. ; [Thrombospondin type-1 domain-containing protein 7A, soluble form]: The soluble form promotes endothelial cell migration and filopodia formation during sprouting angiogenesis via a FAK-dependent mechanism.