产品名称
UROD Rabbit Polyclonal Antibody
蛋白名称
Uroporphyrinogen decarboxylase (UPD) (URO-D) (EC 4.1.1.37)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=7389
Human Swissprot No.
P06132
Human Swissprot Link
https://www.uniprot.org/uniprot/P06132
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=22275
Mouse Swissprot No.
P70697
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/P70697/entry
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/P32362/entry
特异性
This antibody detects endogenous levels of UROD at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
功能
Catalyzes the sequential decarboxylation of the four acetate side chains of uroporphyrinogen to form coproporphyrinogen and participates in the fifth step in the heme biosynthetic pathway . Isomer I or isomer III of uroporphyrinogen may serve as substrate, but only coproporphyrinogen III can ultimately be converted to heme . In vitro also decarboxylates pentacarboxylate porphyrinogen I .