产品名称
TSP3 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
P49746
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P49746/entry
Mouse Swissprot No.
Q05895
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q05895
免疫原
Synthesized peptide derived from part region of human protein
特异性
TSP3 Polyclonal Antibody detects endogenous levels of protein.
宿主
Polyclonal, Rabbit,IgG
背景介绍
thrombospondin 3(THBS3) Homo sapiens The protein encoded by this gene belongs to the thrombospondin family. Thrombospondin family members are adhesive glycoproteins that mediate cell-to-cell and cell-to-matrix interactions. This protein forms a pentameric molecule linked by a single disulfide bond. This gene shares a common promoter with metaxin 1. Alternate splicing results in coding and non-coding transcript variants. [provided by RefSeq, Nov 2011],
组织表达
Lung,PCR rescued clones,Retina,Synovial membrane,
细胞定位
extracellular region,perinuclear region of cytoplasm,
信号通路
TGF-beta;Focal adhesion;ECM-receptor interaction;
功能
function:Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Can bind to fibrinogen, fibronectin, laminin and type V collagen.,similarity:Belongs to the thrombospondin family.,similarity:Contains 1 TSP C-terminal (TSPC) domain.,similarity:Contains 1 TSP N-terminal (TSPN) domain.,similarity:Contains 4 EGF-like domains.,similarity:Contains 8 TSP type-3 repeats.,subunit:Oligomer; disulfide-linked.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
