产品名称
FTSJD2 Rabbit Polyclonal Antibody
基因名称
FTSJD2 KIAA0082 MTR1
蛋白名称
Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 (EC 2.1.1.57) (Cap1 2'O-ribose methyltransferase 1) (MTr1) (hMTr1) (FtsJ methyltransferase domain-containing protein 2) (Interferon-stimulated gene 95 kDa protein) (ISG95)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=23070
Human Swissprot No.
Q8N1G2
Human Swissprot Link
https://www.uniprot.org/uniprot/Q8N1G2
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=74157
Mouse Swissprot No.
Q9DBC3
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9DBC3/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=309656
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q5U2Z5/entry
特异性
This antibody detects endogenous levels of FTSJD2 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
功能
S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap1 2'-O-ribose methylation to the 5'-cap structure of mRNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG-capped mRNA and small nuclear RNA (snRNA) to produce m(7)GpppRm (cap1). Displays a preference for cap0 transcripts. Cap1 modification is linked to higher levels of translation. May be involved in the interferon response pathway.