产品名称
SNPH Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
O15079
Human Swissprot Link
https://www.uniprot.org/uniprotkb/O15079/entry
Mouse Swissprot No.
Q80U23
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q80U23
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941B5DF41
免疫原
Synthesized peptide derived from part region of human protein
特异性
SNPH Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
Syntaxin-1, synaptobrevin/VAMP, and SNAP25 interact to form the SNARE complex, which is required for synaptic vesicle docking and fusion. The protein encoded by this gene is membrane-associated and inhibits SNARE complex formation by binding free syntaxin-1. Expression of this gene appears to be brain-specific. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015],
组织表达
Brain specific. Found in synapses.
细胞定位
Membrane ; Single-pass membrane protein . Cell junction, synapse, synaptosome.
功能
function:Inhibits SNARE complex formation by absorbing free syntaxin-1.,similarity:Belongs to the rad21 family.,subunit:Binds to syntaxin-1.,tissue specificity:Brain specific. Found in synapses.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.