产品名称
SYT8 Rabbit Polyclonal Antibody
蛋白名称
Synaptotagmin-8 (Synaptotagmin VIII) (SytVIII)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q8NBV8
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q8NBV8/entry
Mouse Swissprot No.
Q9R0N6
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9R0N6
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q925B4
免疫原
Synthesized peptide derived from part region of human protein
特异性
SYT8 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the synaptotagmin protein family. Synaptotagmins are membrane proteins that are important in neurotransmission and hormone secretion, both of which involve regulated exocytosis. Expression of the encoded protein in human pancreatic islets has been connected to activity of the promoter for the insulin gene, on the same chromosome several hundred kilobases away (PMID: 21336277 and 22928559). This association would link response to gluclose to insulin secretion. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2014],
组织表达
Lung,Placenta,Testis,
细胞定位
Cell membrane ; Single-pass type III membrane protein . Cytoplasmic vesicle, secretory vesicle, acrosome .
功能
function:Not known. As it is truncated compared to orthologs, its function is not obvious.,sequence caution:The sequence differs from that shown because it is a pre-mRNA.,similarity:Belongs to the synaptotagmin family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
