产品名称
ETF1 Rabbit Polyclonal Antibody
基因名称
ETF1 ERF1 RF1 SUP45L1
蛋白名称
Eukaryotic peptide chain release factor subunit 1 (Eukaryotic release factor 1) (eRF1) (Protein Cl1) (TB3-1)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2107
Human Swissprot No.
P62495
Human Swissprot Link
https://www.uniprot.org/uniprot/P62495
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=225363
Mouse Swissprot No.
Q8BWY3
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8BWY3/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=307503
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q5U2Q7/entry
特异性
This antibody detects endogenous levels of ETF1 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
功能
Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA . Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Required for SHFL-mediated translation termination which inhibits programmed ribosomal frameshifting (-1PRF) of mRNA from viruses and cellular genes .