产品名称
SYT4 Rabbit Polyclonal Antibody
蛋白名称
Synaptotagmin-4 (Synaptotagmin IV) (SytIV)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9H2B2
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9H2B2/entry
Mouse Swissprot No.
P40749
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P40749
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941P50232
免疫原
Synthesized peptide derived from part region of human protein
特异性
SYT4 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
cofactor:Binds 3 calcium ions per subunit. The ions are bound to the C2 domains.,function:May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis.,similarity:Belongs to the synaptotagmin family.,similarity:Contains 2 C2 domains.,tissue specificity:Expressed in brain. Within brain, expression is highest in hippocampus, with substantial levels also detected in amygdala and thalamus.,
组织表达
Expressed in melanocytes (PubMed:23999003). Expressed in brain. Within brain, expression is highest in hippocampus, with substantial levels also detected in amygdala and thalamus (PubMed:23999003).
细胞定位
Cytoplasmic vesicle, secretory vesicle, neuronal dense core vesicle membrane ; Single-pass membrane protein .
功能
cofactor:Binds 3 calcium ions per subunit. The ions are bound to the C2 domains.,function:May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis.,similarity:Belongs to the synaptotagmin family.,similarity:Contains 2 C2 domains.,tissue specificity:Expressed in brain. Within brain, expression is highest in hippocampus, with substantial levels also detected in amygdala and thalamus.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
