产品名称
SYT3 Rabbit Polyclonal Antibody
蛋白名称
Synaptotagmin-3 (Synaptotagmin III) (SytIII)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9BQG1
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9BQG1/entry
Mouse Swissprot No.
O35681
Mouse Swissprot Link
http://www.uniprot.org/uniprot/O35681
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941P40748
免疫原
Synthesized peptide derived from part region of human protein
特异性
SYT3 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
cofactor:Binds 3 calcium ions per subunit. The ions are bound to the C2 domains.,domain:The first C2 domain mediates Ca(2+)-dependent phospholipid binding.,function:May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis.,similarity:Belongs to the synaptotagmin family.,similarity:Contains 2 C2 domains.,subunit:Homodimer. Can also form heterodimers.,
组织表达
Expressed in melanocytes (PubMed:23999003).
细胞定位
Cell membrane ; Single-pass membrane protein . Cytoplasmic vesicle, secretory vesicle membrane ; Single-pass membrane protein .
功能
cofactor:Binds 3 calcium ions per subunit. The ions are bound to the C2 domains.,domain:The first C2 domain mediates Ca(2+)-dependent phospholipid binding.,function:May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis.,similarity:Belongs to the synaptotagmin family.,similarity:Contains 2 C2 domains.,subunit:Homodimer. Can also form heterodimers.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
