产品名称
CYTSA Rabbit Polyclonal Antibody
基因名称
SPECC1L CYTSA KIAA0376
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/23384
Human Swissprot No.
Q69YQ0
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q69YQ0/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/74392
Mouse Swissprot No.
Q2KN98
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q2KN98
Rat Gene Link
https://www.uniprot.org/uniprot/361828
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q2KN99
免疫原
Synthesized peptide derived from human CYTSA AA range: 150-200
特异性
This antibody detects endogenous levels of CYTSA at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a coiled-coil domain containing protein. The encoded protein may play a critical role in actin-cytoskeletal reorganization during facial morphogenesis. Mutations in this gene are a cause of oblique facial clefting-1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A read-through transcript composed of SPECC1L (sperm antigen with calponin homology and coiled-coil domains 1-like) and the downstream ADORA2A (adenosine A2a receptor) gene sequence has been identified, but it is thought to be non-coding. [provided by RefSeq, Jun 2013],
细胞定位
Cytoplasm, cytoskeleton . Cytoplasm, cytoskeleton, spindle . Cell junction, gap junction . Colocalizes with acetylated alpha-tubulin, gamma-tubulin and F-actin. Also observed in a ring around gamma-tubulin containing centrioles possibly in the microtubule organizing center.
功能
function:Involved in cytokinesis and spindle organization.,similarity:Belongs to the cytospin-A family.,similarity:Contains 1 CH (calponin-homology) domain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
