产品名称
Cyclophilin E Rabbit Polyclonal Antibody
蛋白名称
Peptidyl-prolyl cis-trans isomerase E (PPIase E) (EC 5.2.1.8) (Cyclophilin E) (Cyclophilin-33) (Rotamase E)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10450
Human Swissprot No.
Q9UNP9
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9UNP9
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=56031
Mouse Swissprot No.
Q9QZH3
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9QZH3/entry
特异性
This antibody detects endogenous levels of Cyclophilin E at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Found in all the examined tissues including heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
功能
Involved in pre-mRNA splicing as component of the spliceosome . Combines RNA-binding and PPIase activities . Binds mRNA and has a preference for single-stranded RNA molecules with poly-A and poly-U stretches, suggesting it binds to the poly(A)-region in the 3'-UTR of mRNA molecules . Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins . Inhibits KMT2A activity; this requires proline isomerase activity .
