产品名称
ACTR3B Rabbit Polyclonal Antibody
蛋白名称
Actin-related protein 3B (ARP3-beta) (Actin-like protein 3B) (Actin-related protein ARP4)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=57180
Human Swissprot No.
Q9P1U1
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9P1U1
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=242894
Mouse Swissprot No.
Q641P0
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q641P0/entry
特异性
This antibody detects endogenous levels of ACTR3B at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Detected in fetal brain. Detected throughout the adult brain, in neurons from gray matter, but not in white matter. Detected in liver, skeletal muscle and pancreas. Detected in lung adenocarcinoma cells with low metastatic potential, but not in lung adenocarcinoma cells with high metastatic potential.
细胞定位
Cytoplasm, cytoskeleton . Cell projection .
功能
Plays a role in the organization of the actin cytoskeleton. May function as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. May decrease the metastatic potential of tumors.