产品名称
ACBD3 Rabbit Polyclonal Antibody
基因名称
ACBD3 GCP60 GOCAP1 GOLPH1
蛋白名称
Golgi resident protein GCP60 (Acyl-CoA-binding domain-containing protein 3) (Golgi complex-associated protein 1) (GOCAP1) (Golgi phosphoprotein 1) (GOLPH1) (PBR- and PKA-associated protein 7) (Peripheral benzodiazepine receptor-associated protein PAP7)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=64746
Human Swissprot No.
Q9H3P7
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9H3P7
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=170760
Mouse Swissprot No.
Q8BMP6
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8BMP6/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=289312
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q7TNY6/entry
特异性
This antibody detects endogenous levels of ACBD3 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Ubiquitous, with highest expression in testis and ovary.
细胞定位
Golgi apparatus membrane ; Peripheral membrane protein ; Cytoplasmic side . Mitochondrion . Also mitochondrial (via its interaction with PBR). .
功能
Involved in the maintenance of Golgi structure by interacting with giantin, affecting protein transport between the endoplasmic reticulum and Golgi . Involved in hormone-induced steroid biosynthesis in testicular Leydig cells (By similarity). Recruits PI4KB to the Golgi apparatus membrane; enhances the enzyme activity of PI4KB activity via its membrane recruitment thereby increasing the local concentration of the substrate in the vicinity of the kinase . ; (Microbial infection) Plays an essential role in Aichi virus RNA replication by recruiting PI4KB at the viral replication sites.