产品名称
HS2ST1 Rabbit Polyclonal Antibody
基因名称
HS2ST1 HS2ST KIAA0448
蛋白名称
Heparan sulfate 2-O-sulfotransferase 1 (2-O-sulfotransferase) (2OST) (EC 2.8.2.-)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=9653
Human Swissprot No.
Q7LGA3
Human Swissprot Link
https://www.uniprot.org/uniprot/Q7LGA3
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=23908
Mouse Swissprot No.
Q8R3H7
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8R3H7/entry
特异性
This antibody detects endogenous levels of HS2ST1 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Golgi apparatus membrane ; Single-pass type II membrane protein .
功能
Catalyzes the transfer of sulfate to the C2-position of selected hexuronic acid residues within the maturing heparan sulfate (HS). 2-O-sulfation within HS, particularly of iduronate residues, is essential for HS to participate in a variety of high-affinity ligand-binding interactions and signaling processes. Mediates 2-O-sulfation of both L-iduronyl and D-glucuronyl residues (By similarity).