产品名称
SYT14 Rabbit Polyclonal Antibody
蛋白名称
Synaptotagmin-14 (Synaptotagmin XIV) (SytXIV)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q8NB59
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q8NB59/entry
Mouse Swissprot No.
Q7TN84
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q7TN84
免疫原
Synthesized peptide derived from part region of human protein
特异性
SYT14 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
synaptotagmin 14(SYT14) Homo sapiens This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that mediate membrane trafficking in synaptic transmission. The encoded protein is a calcium-independent synaptotagmin. Mutations in this gene are a cause of autosomal recessive spinocerebellar ataxia-11 (SCAR11), and a t(1;3) translocation of this gene has been associated with neurodevelopmental abnormalities. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 4. [provided by RefSeq, Dec 2011],
组织表达
Highly expressed in fetal and adult brain tissue.
细胞定位
Membrane ; Single-pass type III membrane protein . Localized in perinuclear and submembranous regions.
功能
function:May be involved in the trafficking and exocytosis of secretory vesicles in non-neuronal tissues. Is Ca(2+)-independent.,similarity:Belongs to the synaptotagmin family.,similarity:Contains 2 C2 domains.,subunit:Homodimer. Can also form heterodimers.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
