产品名称
SOLO Rabbit Polyclonal Antibody
蛋白名称
SEC14 domain and spectrin repeat-containing protein 1 (Huntingtin-interacting protein-like protein) (Protein Solo)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=91404
Human Swissprot No.
Q86VW0
Human Swissprot Link
https://www.uniprot.org/uniprot/Q86VW0
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=228071
Mouse Swissprot No.
Q80UK0
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q80UK0/entry
特异性
This antibody detects endogenous levels of SOLO at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Broad expression. High expression in thalamus and brain. Significantly expressed in vasculature.
功能
May act as the primary docking protein directing membrane turnover and assembly of the transient receptor potential channels TRPC4 and TRPC5. Binds phospholipids such as phosphatidylinositol monophosphates, phosphatidylinositol diphosphates (PIP2s) and phosphatidic acid, but not less polar lipids including phosphatidylcholine, phosphatidylserine, and phosphatidylinositol. The binding to PIP2s is calcium dependent. Might be involved in the plasma membrane localization of CTNNB1.
