产品名称
NARS Rabbit Polyclonal Antibody
蛋白名称
Asparagine--tRNA ligase, cytoplasmic (EC 6.1.1.22) (Asparaginyl-tRNA synthetase) (AsnRS)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4677
Human Swissprot No.
O43776
Human Swissprot Link
https://www.uniprot.org/uniprot/O43776
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=70223
Mouse Swissprot No.
Q8BP47
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8BP47/entry
特异性
This antibody detects endogenous levels of NARS at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
功能
Catalyzes the attachment of asparagine to tRNA(Asn) in a two-step reaction: asparagine is first activated by ATP to form Asn-AMP and then transferred to the acceptor end of tRNA(Asn) . In addition to its essential role in protein synthesis, acts as a signaling molecule that induced migration of CCR3-expressing cells . Has an essential role in the development of the cerebral cortex, being required for proper proliferation of radial glial cells .