产品名称
UBLCP1 Rabbit Polyclonal Antibody
蛋白名称
Ubiquitin-like domain-containing CTD phosphatase 1 (EC 3.1.3.16) (Nuclear proteasome inhibitor UBLCP1)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=134510
Human Swissprot No.
Q8WVY7
Human Swissprot Link
https://www.uniprot.org/uniprot/Q8WVY7
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=79560
Mouse Swissprot No.
Q8BGR9
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8BGR9/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=360514
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q5FWT7/entry
特异性
This antibody detects endogenous levels of UBLCP1 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Broadly expressed, with highest levels in placenta, lung, testis and ovary. Up-regulated in tumor tissues.
细胞定位
Nucleus . Colocalizes with nuclear proteasomes.
功能
Dephosphorylates 26S nuclear proteasomes, thereby decreasing their proteolytic activity. The dephosphorylation may prevent assembly of the core and regulatory particles (CP and RP) into mature 26S proteasome.