产品名称
KIAA0528 Rabbit Polyclonal Antibody
蛋白名称
Uncharacterized protein KIAA0528
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=9847
Human Swissprot No.
Q86YS7
Human Swissprot Link
https://www.uniprot.org/uniprot/Q86YS7
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=74741
Mouse Swissprot No.
Q7TPS5
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q7TPS5/entry
特异性
This antibody detects endogenous levels of KIAA0528 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Cytoplasmic vesicle membrane . Cytoplasm, cell cortex . Cell membrane . Cell projection, ruffle . Dynamically associated with GLUT4-containing glucose storage vesicles (GSV) and plasma membrane in response to insulin stimulation.
功能
Required for insulin-stimulated glucose transport and glucose transporter SLC2A4/GLUT4 translocation from intracellular glucose storage vesicle (GSV) to the plasma membrane (PM) in adipocytes. Binds phospholipid membranes in a calcium-dependent manner and is necessary for the optimal membrane fusion between SLC2A4/GLUT4 GSV and the PM.
