产品名称
NT5M Rabbit Polyclonal Antibody
蛋白名称
5'(3')-deoxyribonucleotidase, mitochondrial (5',3'-nucleotidase, mitochondrial) (EC 3.1.3.-) (Deoxy-5'-nucleotidase 2) (dNT-2)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=56953
Human Swissprot No.
Q9NPB1
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9NPB1
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=103850
Mouse Swissprot No.
Q8VCE6
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8VCE6/entry
特异性
This antibody detects endogenous levels of NT5M at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Highly expressed in heart, brain and skeletal muscle. Detected at very low levels in kidney and pancreas.
功能
Dephosphorylates specifically the 5' and 2'(3')-phosphates of uracil and thymine deoxyribonucleotides, and so protects mitochondrial DNA replication from excess dTTP. Has only marginal activity towards dIMP and dGMP.