产品名称
MTMR2 Rabbit Polyclonal Antibody
蛋白名称
Myotubularin-related protein 2 (EC 3.1.3.-)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=8898
Human Swissprot No.
Q13614
Human Swissprot Link
https://www.uniprot.org/uniprot/Q13614
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=77116
Mouse Swissprot No.
Q9Z2D1
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9Z2D1/entry
特异性
This antibody detects endogenous levels of MTMR2 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Cytoplasm . Early endosome membrane ; Peripheral membrane protein . Cytoplasm, perinuclear region . Cell projection, axon . Endosome membrane ; Peripheral membrane protein . Partly associated with membranes (PubMed:12668758, PubMed:15998640, PubMed:21372139). Localizes to vacuoles in hypo-osmotic conditions (By similarity). .
功能
Phosphatase that acts on lipids with a phosphoinositol headgroup. Has phosphatase activity towards phosphatidylinositol 3-phosphate and phosphatidylinositol 3,5-bisphosphate . Binds phosphatidylinositol 4-phosphate, phosphatidylinositol 5-phosphate, phosphatidylinositol 3,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate (By similarity). Stabilizes SBF2/MTMR13 at the membranes (By similarity). Specifically in peripheral nerves, stabilizes SBF2/MTMR13 protein (By similarity).
