产品名称
DCDC2 Rabbit Polyclonal Antibody
蛋白名称
Doublecortin domain-containing protein 2 (Protein RU2S)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=51473
Human Swissprot No.
Q9UHG0
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9UHG0
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=195208
Mouse Swissprot No.
Q5DU00
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q5DU00/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=291130
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/D3ZR10/entry
特异性
This antibody detects endogenous levels of DCDC2 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Ubiquitously expressed. In brain, highly expressed in the entorhinal cortex, inferior temporal cortex, medial temporal cortex, hypothalamus, amygdala and hippocampus (PubMed:10601354, PubMed:16278297). Expressed in liver by cholangiocytes, the epithelial cells of the bile ducts (at protein level) (PubMed:27319779).
细胞定位
Cell projection, cilium . Cytoplasm, cytoskeleton, cilium axoneme . Cell projection, kinocilium . Cytoplasm, cytoskeleton . Localizes to the ciliary axoneme and to mitotic spindle fibers in a cell-cycle-dependent manner. .
功能
Protein that plays a role in the inhibition of canonical Wnt signaling pathway . May be involved in neuronal migration during development of the cerebral neocortex (By similarity). Involved in the control of ciliogenesis and ciliary length .
